Extracellular matrix, integrins, and focal adhesion signaling in polycystic kidney disease

Y Zhang, G Reif, DP Wallace - Cellular signalling, 2020 - Elsevier
… of renal cyst development in polycystic kidney disease (PKD). … ducts, whereas the α 6 -subunit
is expressed in all nephron … 1 -subunit in precystic and cystic collecting duct cells in fetal

[HTML][HTML] Emerging therapies for autosomal dominant polycystic kidney disease with a focus on cAMP signaling

X Zhou, VE Torres - Frontiers in Molecular Biosciences, 2022 - frontiersin.org
… specific expression of constitutively active AMPK, with a gain-of-function mutation in the
AMPKγ1 subunit, resulted in an early-onset polycystic kidney phenotype with collecting duct cysts…

Proteomics of Serum Samples for the Exploration of the Pathological Mechanism of Obstetric Antiphospholipid Syndrome

Y Zhang, S Jin, W Tian, D Shi, Y Chen… - Journal of Proteome …, 2023 - ACS Publications
… (OAPS) is a multisystem disorder characterized by thrombosis or recurrent fetal loss. In this
… KEGG pathways related to autoimmune diseases, allergic diseases, and pathogen infection. …

Collagen type XI alpha 1 (COL11A1): a novel biomarker and a key player in cancer

S Nallanthighal, JP Heiserman, DJ Cheon - Cancers, 2021 - mdpi.com
… terminal domain (NTD) of COL11A1 in fetal bovine cartilage, which is displayed at the …
integrin heterodimers (alpha integrin subunits α1, α2, α10, α11 paired with the β1 integrin subunit), …

[HTML][HTML] The formin DAAM1 regulates the deubiquitinase activity of USP10 and integrin homeostasis

AT Phillips, EF Boumil, A Venkatesan… - European Journal of …, 2023 - Elsevier
… due to protein cleavage/breakdown. To assess the level of … subunits (β1 and β5), we tested
how DAAM1 siRNA altered integrin ubiquitin status. For both β1 and β5-integrin subunits, we …

Daam1 negatively regulates USP10 activity

AT Phillips, EF Boumil, A Venkatesan, N Castro… - bioRxiv, 2022 - biorxiv.org
… We predicted that a random distribution of Daam1 and USP10 … Thus, Daam1 transitioned
from a distribution that was, on … in HCFs, we analyzed integrin subunit protein levels without or …

[HTML][HTML] The pig as a model for immunology research

R Pabst - Cell and tissue research, 2020 - Springer
… be optimal when the organ distribution and age dependence … However, Intrauterine injection
of fetal and germfree pigs with … The alpha integrin C11R1 was most frequently expressed. …

The role of Protein kinase D1 in progression and metastasis of pancreatic ductal adenocarcinoma

CD Steup - 2022 - oparu.uni-ulm.de
… (A) fold regulation of alpha integrin family (B) fold regulation of beta integrin family. The
fold regulation was calculated using the 2-ΔΔCt-method comparing Prk1KC to KC cell lines (n=3 …

Sex-specific Impact of 17β-estradiol and Testosterone Levels on Inflammation and Injury in Acute Myocardial Infarction

NE Semerdzhieva, AD Tsakova, J Hristova… - 2023 - preprints.org
… The distribution of these gangliosides supports the capability of MuPyV to infect brain tissue
… CD103 is an alpha integrin considered to be a broad marker of TRM cells [290]. Wild-type …

[HTML][HTML] Polyomavirus wakes up and chooses neurovirulence

AB Butic, SA Spencer, SK Shaheen, AE Lukacher - Viruses, 2023 - mdpi.com
… The distribution of these gangliosides supports the capability of MuPyV to infect the brain …
CD103 is an alpha integrin considered to be a broad marker of T RM cells [291]. Wild-type mice …